Check out this
review essay in Cell:
Genetic Heterogeneity in Human Disease, by Jon McClellan and Mary-Claire King. (King's lab, incidentally, was the group who
discovered via linkage analysis that the gene for early-onset breast and ovarian cancer on chromosome 17q21, nearly 5 years before Myriad Genetics filed for
patent protection on the BRCA1/2 genes). Anyhow, looks like a great review on genetic heterogeneity and
GWAS. Thanks
@JVJAI.
Cell: Genetic Heterogeneity in Human Disease
UPDATE 4/16/2010: See my synopsis and thoughts on this essay
here.
UPDATE 4/29/2010: See further thoughts on this essay
here.
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