Thursday, May 7, 2009
Gene regulation: A new toolbox for mapping regulatory sites
Here's a paper in Nature Reviews Genetics highlighting two recently published methods for mapping regulatory sites. Most currently used procedures rely on ChIP, where you can only examine sites one protein at a time. The two methods discussed here can potentially overcome these limitations - one mostly identifies cis-regulatory sites near promoters, and the other is capable of identifying sites farther away, including long range enhancer elements.
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