Getting Genetics Done

I talked a little bit about tidy data my recent post about dplyr , but you should really go check out Hadley’s paper on the subject . R ...

Two years ago David Searls published an article in PLoS Comp Bio describing a series of online courses in bioinformatics. Yesterday, the sa...

I first mentioned Coursera about a year ago , when I hired a new analyst in my core. This new hire came in as a very competent Python progra...

Jeff Leek , biostats professor at Johns Hopkins and instructor of the Coursera Data Analysis course , recently posted on Simly Statistics th...

Since the near beginning of genome-wide association studies, the PLINK software package (developed by Shaun Purcell’s group at the B...

Two of the most common questions at the beginning of an RNA-seq experiments are "how many reads do I need?" and "how many rep...

About a year ago I wrote a post about producing scatterplot matrices in R . These are handy for quickly getting a sense of the correlations ...

I haven't posted much here recently, but here is a roundup of a few of the links I've shared on Twitter ( @genetics_blog ) over the ...

In my previous post I showed you how to randomly split up a dataset into training and testing datasets. (Thanks to all those who emailed me...

When I have a question I usually ask the internet before bugging my neighbor. Yet it seems like Google's search results have become incr...

I thought it would be trivial to extract the p-value on the F-test of a linear regression model (testing the null hypothesis R²=0). If I fit...

I was recently reading a bit about logistic regression in Gelman and Hill's book on hierarchical/multilevel modeling when I first learn...

I've had friends in biochem "wet" labs who've asked me to do some simple statistics on some of their results. This looks l...

Found this tutorial by Emily Mankin on how to do principal components analysis (PCA) using R . Has a nice example with R code and several go...

Several readers emailed me or left a comment on my previous announcement of Frank Harrell's workshop on using Sweave for reproducibl...

If you attended Frank Harrell's Regression Modeling Strategies course a few weeks ago, you got a chance to see the rms package for R ...

Update 2010-04-21 : I forgot to post the link last time. That would have been helpful. Here you go: Vanderbilt Biostatistics: Statistical ...

This month's cancer biostatistics workshop on overfitting will be given by Fei Ye and Zhiguo (Alex) Zhao, both in the Department of Bios...

I recently did an analysis for the eMERGE network where I had lots of individuals from a small town in central Wisconsin where many of the ...

I've been using GenABEL for some time now for GWAS analysis using related individuals. It has an excellent set of functions for estimati...