Getting Genetics Done

I just returned from the  Genome Informatics meeting  at Cold Spring Harbor. This was, hands down, the best scientific conference I've ...

Last week I ran a one-day workshop on RNA-seq data analysis in the UVA Health Sciences Library. I set up an AWS public EC2 image with all th...

Last week I taught a three-hour introduction to R workshop for life scientists at UVA's Health Sciences Library. I broke the works...

I've been asked a few times how to make a so-called volcano plot from gene expression results. A volcano plot typically plots some meas...

Jeff Leek , biostats professor at Johns Hopkins and instructor of the Coursera Data Analysis course , recently posted on Simly Statistics th...

RNA-seq has been performed routinely for at least 5+ years , yet there is no consensus on the best methodology for analyzing this data. For ...

One of the clearest advantages RNA-seq has over array-based technology for studying gene expression is not needing a reference genome or a p...

I collaborate with several investigators on gene expression projects using both microarray and RNA-seq. After I show a collaborator which ge...

Automatically Archiving Twitter Results Ever since Twitter gamed its own API and killed off great services like IFTTT triggers , I've...

Two of the most common questions at the beginning of an RNA-seq experiments are "how many reads do I need?" and "how many rep...

In case you missed it, a new paper was published in Nature Biotechnology on a method for detecting isoform-level differential expression wit...

There's a new kid on the block for RNA-seq alignment. Dobin, Alexander, et al. "STAR: ultrafast universal RNA-seq aligner." ...

Update (Dec 18, 2012): Please see this related post I wrote about differential isoform expression analysis with Cuffdiff 2 . DESeq and e...

I just got this announcement from EMBL-EBI about an RNA-seq/ChIP-seq analysis hands-on course. Find the full details, schedule, and speaker ...

I found the slides below on the education page from Bioinformatics & Research Computing at the Whitehead Institute. The first set ( PDF...

James Taylor came to UVA last week and gave an excellent talk on how Galaxy enables transparent and reproducible research in genomics. I...